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Wolsong 1 resumes operation following licence extension

World Nuclear News - Wed, 06/24/2015 - 08:56
Unit 1 of South Korea's Wolsong nuclear power plant restarted yesterday after having been offline since November 2012 when its operating licence expired. A new licence was issued in February.

UK MET Office: Fastest decline in solar activity since the last ice age

Climate Depot - Wed, 06/24/2015 - 08:16
http://wattsupwiththat.com/2015/06/24/uk-met-fastest-decline-solar-activity-last-ice-age/

Matt Ridley: ‘Thanks largely to climate science, I see bad ideas can persist for decades…become intolerant dogmas’

Climate Depot - Wed, 06/24/2015 - 07:03
http://quadrant.org.au/magazine/2015/06/climate-wars-done-science/

Study: Weak sun could offset some global warming in Europe and US

Climate Depot - Tue, 06/23/2015 - 19:19
http://www.theguardian.com/environment/2015/jun/23/weak-sun-could-offset-some-global-warming-europe-us-study Global warming in northern Europe and the eastern US could be partially offset in future winters because of the sun entering a weaker cycle similar to the one which enabled frost fairs to take place on the river Thames in the 17th and 18th century, according to new research. However, the study said any [...]

Britain faces FREEZING winters as slump in solar activity threatens ‘little Ice Age’

Climate Depot - Tue, 06/23/2015 - 18:54
http://www.express.co.uk/news/nature/586404/Britain-freezing-winters-slump-solar-activity Climate experts warn the amount of light and warmth released by the sun is nosediving to levels “not seen for centuries”. They fear a repeat of the so-called ‘Maunder Minimum’ which triggered Arctic winter whiteouts and led to the River Thames freezing 300 years ago. The Met Office-led study warns although the effect will [...]

EPA Chief: ‘Climate Deniers’ Aren’t ‘Normal’

Climate Depot - Tue, 06/23/2015 - 18:00
http://dailycaller.com/2015/06/23/epa-chief-climate-deniers-arent-normal-human-beings/   EPA Administrator Gina McCarthy told an audience Tuesday gathered at a White House conference “normal people,” not “climate deniers” will win the debate on global warming. McCarthy’s remarks came as she was talking about the reasons why the EPA put out a report on the negative health impacts global warming will have on [...]

EOn supports early closure of Oskarshamn units

World Nuclear News - Tue, 06/23/2015 - 09:53
Unit 2 of the Oskarshamn nuclear power plant in Sweden would close by 2020, with unit 1 shutting between 2017 and 2019, under a proposal announced today by majority owner EOn. Minority owner Fortum opposes the early shutdown of the units.

Canadian government approves overseas ownership

World Nuclear News - Tue, 06/23/2015 - 09:37
The Canadian government has approved Australian majority ownership of the proposed Michelin uranium mine, in an exception to Canadian legislation on overseas ownership in commercial mining operations.

Dynamic connectivity predicts behavior [Neuroscience]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Most brain activity occurs in an ongoing manner not directly locked to external events or stimuli. Regional ongoing activity fluctuates in unison with some brain regions but not others, and the degree of long-range coupling is called functional connectivity, often measured with correlation. Strength and spatial distributions of functional connectivity...

Backbones of evolutionary history [Ecology]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Identifying the ecological and evolutionary mechanisms that determine biological diversity is a central question in ecology. In microbial ecology, phylogenetic diversity is an increasingly common and relevant means of quantifying community diversity, particularly given the challenges in defining unambiguous species units from environmental sequence data. We explore patterns of phylogenetic...

CD14-independent TLR4 endocytosis and signaling [Immunology and Inflammation]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Dimerization of Toll-like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD2) heterodimers is critical for both MyD88- and TIR-domain–containing adapter-inducing IFN-β (TRIF)-mediated signaling pathways. Recently, Zanoni et al. [(2011) Cell 147(4):868–880] reported that cluster of differentiation 14 (CD14) is required for LPS-/Escherichia coli- induced TLR4 internalization into endosomes and activation of...

Class III preQ1 riboswitch structure and dynamics [Biophysics and Computational Biology]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
PreQ1-III riboswitches are newly identified RNA elements that control bacterial genes in response to preQ1 (7-aminomethyl-7-deazaguanine), a precursor to the essential hypermodified tRNA base queuosine. Although numerous riboswitches fold as H-type or HLout-type pseudoknots that integrate ligand-binding and regulatory sequences within a single folded domain, the preQ1-III riboswitch aptamer forms...

Selective and inducible proteolysis in cells [Cell Biology]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Cellular demolition during apoptosis is completed by executioner caspases, that selectively cleave more than 1,500 proteins but whose individual roles are challenging to assess. Here, we used an optimized site-specific and inducible protease to examine the role of a classic apoptotic node, the caspase-activated DNase (CAD). CAD is activated when...

Arabidopsis CRY1 and photoreduction [Plant Biology]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Cryptochromes in different evolutionary lineages act as either photoreceptors or light-independent transcription repressors. The flavin cofactor of both types of cryptochromes can be photoreduced in vitro by electron transportation via three evolutionarily conserved tryptophan residues known as the “Trp triad.” It was hypothesized that Trp triad-dependent photoreduction leads directly to...

PSIA to predict biosynthetic pathways [Biochemistry]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Tramadol, previously only known as a synthetic analgesic, has now been found in the bark and wood of roots of the African medicinal tree Nauclea latifolia. At present, no direct evidence is available as to the biosynthetic pathway of its unusual skeleton. To provide guidance as to possible biosynthetic precursors,...

Vitamin A dimerization triggers RPE lipofuscin [Medical Sciences]

PNAS Early Edition Articles - Tue, 06/23/2015 - 09:34
Stargardt disease, an ATP-binding cassette, subfamily A, member 4 (ABCA4)-related retinopathy, is a genetic condition characterized by the accelerated accumulation of lipofuscin in the retinal pigment epithelium, degeneration of the neuroretina, and loss of vision. No approved treatment exists. Here, using a murine model of Stargardt disease, we show that...
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