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C-C bond scission by cytochrome P450 OleT [Chemistry]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
OleT is a cytochrome P450 that catalyzes the hydrogen peroxide-dependent metabolism of Cn chain-length fatty acids to synthesize Cn-1 1-alkenes. The decarboxylation reaction provides a route for the production of drop-in hydrocarbon fuels from a renewable and abundant natural resource. This transformation is highly unusual for a P450, which typically...

Single-cell live imaging of growing biofilms [Microbiology]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Biofilms are surface-associated bacterial communities that are crucial in nature and during infection. Despite extensive work to identify biofilm components and to discover how they are regulated, little is known about biofilm structure at the level of individual cells. Here, we use state-of-the-art microscopy techniques to enable live single-cell resolution...

PLEKHG3 enhances cell polarity by activating Rac1 [Cell Biology]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Cells migrate by directing Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42) activities and by polymerizing actin toward the leading edge of the cell. Previous studies have proposed that this polarization process requires a local positive feedback in the leading edge involving Rac small...

Phage Mu baseplate assembly [Microbiology]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Contractile phage tails are powerful cell puncturing nanomachines that have been co-opted by bacteria for self-defense against both bacteria and eukaryotic cells. The tail of phage T4 has long served as the paradigm for understanding contractile tail-like systems despite its greater complexity compared with other contractile-tailed phages. Here, we present...

Cytosolic activity of cereal rust resistance NLRs [Plant Biology]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Plants possess intracellular immune receptors designated “nucleotide-binding domain and leucine-rich repeat” (NLR) proteins that translate pathogen-specific recognition into disease-resistance signaling. The wheat immune receptors Sr33 and Sr50 belong to the class of coiled-coil (CC) NLRs. They confer resistance against a broad spectrum of field isolates of Puccinia graminis f. sp....

E3-ligase Mid1 clears Pax6 from the optic stalk [Developmental Biology]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Pax6 is a key transcription factor involved in eye, brain, and pancreas development. Although pax6 is expressed in the whole prospective retinal field, subsequently its expression becomes restricted to the optic cup by reciprocal transcriptional repression of pax6 and pax2. However, it remains unclear how Pax6 protein is removed from...

Fundamental structures of dynamic social networks [Social Sciences]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Social systems are in a constant state of flux, with dynamics spanning from minute-by-minute changes to patterns present on the timescale of years. Accurate models of social dynamics are important for understanding the spreading of influence or diseases, formation of friendships, and the productivity of teams. Although there has been...

Price of complexity in financial networks [Physics]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Financial institutions form multilayer networks by engaging in contracts with each other and by holding exposures to common assets. As a result, the default probability of one institution depends on the default probability of all of the other institutions in the network. Here, we show how small errors on the...

Rich gets simpler [Commentaries]

PNAS Early Edition Articles - Tue, 08/23/2016 - 09:14
Network science plays a central role in the study of complex systems, offering a range of computational tools and, importantly, a common language to represent systems as diverse as the World Wide Web, the human brain, and social networks (1). Within the framework of network science, a system is modeled...

Largest module in place at second Vogtle AP1000

World Nuclear News - Tue, 08/23/2016 - 09:08
The largest module has been installed at the Vogtle 4 nuclear construction project in the US state of Georgia. Emplacement of the CA20 module marks the heaviest lift at the project so far this year.

US advanced reactor developers team up

World Nuclear News - Tue, 08/23/2016 - 08:37
X-energy and Southern Nuclear Operating Company have signed a memorandum of understanding to collaborate on development and commercialization of their respective advanced reactor designs.

Study finds West Antarctica snow accumulation ‘increased dramatically’ 30% from 1900-2010

Climate Depot - Tue, 08/23/2016 - 07:56
West Antarctic coastal snow accumulation rose 30 percent during 20th century Date: November 4, 2015 Source: American Geophysical Union Summary: Annual snow accumulation on West Antarctica’s coastal ice sheet increased dramatically during the 20th century, according to a new study. The research gives scientists new insight into Antarctica’s blanket of ice. Understanding how the ice [...]

Global Warming Alarmists Plead: Save the Children By Not Having Them

Climate Depot - Tue, 08/23/2016 - 07:15
https://stream.org/global-warming-alarmists-plead-save-children-by-not-having-them/ Our greatest natural disasters occurred long ago before global warming loomed, (as this site documents). In 1931, a flood killed perhaps two million Chinese. Forest fires in the USA are far, far below their destructive peak in the late 1920s. An awful flood happened in 1936, the same year a heat-wave killed some 12,000 [...]

Ignalina turbine hall dismantling completed

World Nuclear News - Tue, 08/23/2016 - 04:24
Work that began in October 2011 to dismantle the turbine halls of unit 1 of the Ignalina nuclear power plant - or the B9/1 project - has been completed. The dismantled equipment weighs more than 18,000 tonnes and consists mostly of turbines, generators, heat exchangers, pumps, valves and pipes.

Bill Nye Laments climate debate: ‘The deniers have been very successful — surprisingly successful’ 

Climate Depot - Mon, 08/22/2016 - 20:30
http://www.cbsnews.com/news/bill-nye-national-parks-climate-change-2016-election/ CBS News: How come environmental causes — climate change, specifically — have not been brought to the forefront of political debate this year? Domestic, international, and economic issues are at the center, but we really aren’t talking about the environment this cycle. Why is that? Well, first of all, I’m not telling anyone who [...]

1,690-Page ‘Climate Change’ Reg Increases Cost of Tractor-Trailer Up to $15,119

Climate Depot - Mon, 08/22/2016 - 20:24
http://www.cnsnews.com/news/article/terence-p-jeffrey/1690-page-climate-change-regulation-increases-cost-tractor-trailer The Environmental Protection Agency and the National Highway Traffic Safety Administration jointly issued a new regulation last week that is meant to help protect the world from “climate change” by limiting “greenhouse gas emissions” and improving fuel efficiency in medium- and heavy-duty vehicles operated in the United States. The 1,690-page regulation is approximately 700,000 words long. [...]

Fact: ‘Louisiana Floods Not Result of Man-Made Climate Change’

Climate Depot - Mon, 08/22/2016 - 18:12
http://dailysignal.com/2016/08/17/the-facts-show-louisianas-floods-not-caused-by-man-made-climate-change/?utm_source=TDS_Email&utm_medium=email&utm_campaign=MorningBell&mkt_tok=eyJpIjoiTWpka1ptSTRZalZqWmpjdyIsInQiOiJSbjFWWHJVQXpHR2Z3XC9kS3JZSzA1Z2NMQmdLUkorOGRaTm1tWWpRdHllOU9SZTlMOUZWSHBGZ05ORW1qZTFIK096YXUyMFpQOEtzSmJcLzZFem5nMnB6MElYM2U1bWg4dnNrSW95WWpoM1RNPSJ9 But is man-made global warming to blame? Climatologists Patrick Michaels and Paul Knappenberger point to two recent studies that indicate not. In one study, two researchers at the University of Iowa specializing in hydroscience and engineeringconclude that “over the last 65 years, the stronger storms are not getting stronger, but a larger number of heavy precipitation events [...]

Report: Millennials could lose trillions in lifetime income because of ‘climate change’

Climate Depot - Mon, 08/22/2016 - 17:52
Millennials could lose trillions in lifetime income because of climate change 531   Share Tweet  The Blue Cut wildfire burns housings and trees near San Bernardino, California, Aug. 16, 2016. IMAGE: RINGO CHIU/AFP/GETTY IMAGES BY MARIA GALLUCCI2 HOURS AGO Americans in their 20s and 30s could lose trillions of dollars in potential lifetime earnings as climate change [...]
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