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Matrix mechanics controls FHL2 localization [Cell Biology]

PNAS Early Edition Articles - Fri, 10/14/2016 - 16:05
Substrate rigidity affects many physiological processes through mechanochemical signals from focal adhesion (FA) complexes that subsequently modulate gene expression. We find that shuttling of the LIM domain (domain discovered in the proteins, Lin11, Isl-1, and Mec-3) protein four-and-a-half LIM domains 2 (FHL2) between FAs and the nucleus depends on matrix...

Latest On California’s Drought: Total precipitation in past 12 months up slightly above average

Climate Depot - Fri, 10/14/2016 - 12:53
By Paul Homewood http://www.ncdc.noaa.gov/cag/time-series/us/4/0/pcp/12/9/1895-2016?base_prd=true&firstbaseyear=1895&lastbaseyear=2016&filter=true&filterType=binomial Now that NOAA data for September has been published, we can look at Californian precipitation for the last hydrologic year, which runs Oct to Sep. Total precipitation in the last 12 months ended up slightly above average. Prior to this, there was a run of four particularly dry years. Maybe one [...]

‘Electricity prices fudged now – just like temperature’

Climate Depot - Fri, 10/14/2016 - 12:05
by Warwick Hughes AEMO daily Regional Reference Price for South Australia clearly fudged – if this carries on their data will be meaningless. 4th Oct RRP was originally minus $387. Full size table

How Gaia and coral reefs regulate ocean pH

Climate Depot - Fri, 10/14/2016 - 12:03
by Jim Steele Although some researchers have raised concerns about possible negative effects of rising CO2 on ocean surface pH, there are several lines of evidence demonstrating marine ecosystems are far more sensitive to fluxes of carbon dioxide from ocean depths and the biosphere’s response than from invasions of atmospheric CO2. There is also ample [...]


Climate Depot - Fri, 10/14/2016 - 12:01
Veteran Yale University research ecologist Dr. Dan Botkin has a new book coming out tomorrow (Saturday 15 October) that you might want to look at: A number of chapters are relevant to polar bears, including these three: “Myth 11: Without Human Interference, Earth’s Climate is Stable” “Myth 13: Climate Change Will Lead to Huge Numbers of [...]

Leonardo DiCaprio Urged to Step Down From UN Climate Change Role

Climate Depot - Fri, 10/14/2016 - 11:09
A rainforest charity calls on the star to either denounce his connection to individuals involved in a Malaysian corruption scandal and return laundered money he allegedly received or give up his role. In perhaps the biggest attack on Leonardo DiCaprio’s environmental credibility, a rainforest charity on Friday called on the actor to give up his [...]

‘Global Warming’ be Damned: Record Corn, Soybeans, Wheat

Climate Depot - Fri, 10/14/2016 - 11:03
October 14th, 2016 by Roy W. Spencer, Ph. D. For many years we have been warned that climate change is creating a “climate crisis”, with heat and drought reducing agricultural yields to the point that humanity will suffer. Every time there’s a drought, we are told that this is just one more example of human-caused [...]

Feds warn colder winter temps will raise heating bills

Climate Depot - Fri, 10/14/2016 - 10:59
Via: http://us.blastingnews.com/news/2016/10/government-warns-colder-winter-temps-will-raise-heating-bills-001183763.html By THOMAS RICHARD Government warns colder winter temps will raise heating bills DOE analysts announced their winter outlook and are warning Americans to expect a much colder winter and higher heating costs. DOE’s outlook is good for winter enthusiasts. Photo – Pixabay Yesterday, #Government analysts at the Department of Energy said to expect higher [...]

US plants unscathed by Hurricane Matthew

World Nuclear News - Fri, 10/14/2016 - 09:33
Preparations by plant operators, rigorous design and operating procedures and a coordinated industry and government response ensured that nuclear power plants in the south-eastern USA were undamaged by the first major hurricane to hit continental USA in 11 years.

Contract for nuclear islands of Xudabao Phase I

World Nuclear News - Fri, 10/14/2016 - 09:14
A contract has been signed for the civil construction of the nuclear islands for units 1 and 2 of the Xudabao nuclear power plant in China's Liaoning province. The units are the first of six AP1000 reactors planned for the site.

Haiyang 1 pumps operated at full-power

World Nuclear News - Fri, 10/14/2016 - 08:07
The four reactor coolant pumps at unit 1 of the Haiyang nuclear power plant in China's Shandong province have been operated simultaneously at full speed for the first time. The AP1000 is set to begin operating by the end of the year.

Solar Warming? President Obama Issues Order To Battle ‘Space Weather’

Climate Depot - Thu, 10/13/2016 - 15:11
http://www.mrctv.org/blog/solar-warming-president-obama-issues-order-battle-space-weather  Brittany M. Hughes | 45 minutes ago As if all the death, doom and destruction headed our way thanks to manmade climate change isn’t enough, President Obama has launched a new effort to control the latest coming apocalypse – space weather. The issue of deadly “space weather” is so pressing and so perilous to our [...]

Promotion of mouse pluripotency by LPA signaling [Cell Biology]

PNAS Early Edition Articles - Thu, 10/13/2016 - 13:42
Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in multicellular organisms is a key problem in biology. Here, we demonstrate that the combination of leukemia inhibitory factor (LIF), bone morphogenetic protein 4 (BMP4), lysophosphatidic acid (LPA), and...

Hillary’s Claim That Matthew Was Caused By ‘Climate Change’ Refuted By Science

Climate Depot - Thu, 10/13/2016 - 13:25
By Brittany M. Hughes | October 12, 2016 2:19pm ET There are a few glaring problems with Clinton’s premise that Hurricane Matthew was actually worse because of “climate change” – the first and most obvious being the question, worse than what? There was no bare-minimum destruction standard for Matthew, or any other hurricane for that matter. [...]

‘Are Global Warming Alarmists Disappointed Hurricane Matthew Wasn’t Worse?’

Climate Depot - Thu, 10/13/2016 - 12:53
By KERRY JACKSON 10/12/2016 Their impatient craving for a crisis was summed up well two years ago in August when a fellow named Greg Blanchette tweeted that he “kind of” hoped that North America “gets its ass kicked this hurricane season. It would motivate us on climate action.” Is this the same Greg Blanchette who proposed [...]

UN central planners head to Ecuador for “sustainability” conference

Climate Depot - Thu, 10/13/2016 - 11:25
UN central planners head to Ecuador for “sustainability” conference http://www.cfact.org/2016/10/11/un-central-planners-head-to-ecuador-for-sustainability-conference/ They’re at it again. The UN is gearing up once again to convene a major gathering for the purpose of micro-managing our lives — this one is set for next week in South America. — gReader Pro

Anyone who says we’re enduring ‘unprecedented global warming’ is woefully misinformed

Climate Depot - Thu, 10/13/2016 - 10:00
Anyone who says we’re enduring “unprecedented global warming” is lying or woefully misinformed https://iceagenow.info/anyone-says-enduring-unprecedented-global-warming-lying-woefully-misinformed/ It is colder right now than throughout almost all of history. Look at this chart. The blue line shows temperatures for the past 600 million years. Look at the far right side of the chart (today), and you’ll see that blue [...]

Podesta Emails: ‘Pope Is the Real Deal’ on Climate

Climate Depot - Thu, 10/13/2016 - 09:52
Despite leaked emails showing members of Hillary Clinton’s team expressing contempt for Catholics, Clinton campaign chairman John Podesta is apparently fond of Pope Francis because his “Jesuit friends” think the pope is “the real deal” on climate issues. In an email exchange released by WikiLeaks, Podesta spoke to New York City Mayor Bill de Blasio after [...]
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