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CB&I, CNNC extend cooperation

World Nuclear News - Thu, 07/17/2014 - 09:30
US energy infrastructure company CB&I has increased its cooperation with the Chinese nuclear industry by signing a memorandum of understanding with China National Nuclear Corporation (CNNC). The agreement will see them cooperate on the development of nuclear power plants.

Kerry Emanuel Clarifies Quote in the NYT: ‘I have absolutely no reason to question John’s motives; indeed, he strikes me as the sort of person who would risk his own life to save a child who wandered into a busy street’

Climate Depot - Thu, 07/17/2014 - 06:22
Guest Post: Kerry Emanuel Clarifies a Recent Quote in the NYT http://rogerpielkejr.blogspot.com/2014/07/guest-post-kerry-emanuel-clarifies.html The comment below is by Kerry Emanuel, at MIT, who is clarifying a recent quote of his in the New York Times.I would like first to thank Roger for allowing me to post this response to the article about John Christy by Michael [...]

CBS Shamelessly Hypes Climate Change Will Cause More Turbulence For Airplanes

Climate Depot - Wed, 07/16/2014 - 21:15

N-glycans enhance receptor-clathrin interactions [Biophysics and Computational Biology]

PNAS Early Edition Articles - Wed, 07/16/2014 - 13:34
Glycan–protein interactions are emerging as important modulators of membrane protein organization and dynamics, regulating multiple cellular functions. In particular, it has been postulated that glycan-mediated interactions regulate surface residence time of glycoproteins and endocytosis. How this precisely occurs is poorly understood. Here we applied single-molecule-based approaches to directly visualize the...

Allosteric cross-talk in ABC exporters [Biochemistry]

PNAS Early Edition Articles - Wed, 07/16/2014 - 13:34
ATP binding cassette (ABC) transporters mediate vital transport processes in every living cell. ATP hydrolysis, which fuels transport, displays positive cooperativity in numerous ABC transporters. In particular, heterodimeric ABC exporters exhibit pronounced allosteric coupling between a catalytically impaired degenerate site, where nucleotides bind tightly, and a consensus site, at which...

Molecular extraction in single live cells [Physics]

PNAS Early Edition Articles - Wed, 07/16/2014 - 13:34
Extraction of intracellular molecules is crucial to the study of cellular signal pathways. Disruption of the cellular membrane remains the established method to release intracellular contents, which inevitably terminates the time course of biological processes. Also, conventional laboratory extractions mostly use bulky materials that ignore the heterogeneity of each cell....

TMEM129 is a novel ERAD E3 ligase [Immunology]

PNAS Early Edition Articles - Wed, 07/16/2014 - 13:34
The US11 gene product of human cytomegalovirus promotes viral immune evasion by hijacking the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. US11 initiates dislocation of newly translocated MHC I from the ER to the cytosol for proteasome-mediated degradation. Despite the critical role for ubiquitin in this degradation pathway, the responsible E3...

Energy landscapes of {alpha}-helical membrane proteins [Biophysics and Computational Biology]

PNAS Early Edition Articles - Wed, 07/16/2014 - 13:34
We explore the hypothesis that the folding landscapes of membrane proteins are funneled once the proteins’ topology within the membrane is established. We extend a protein folding model, the associative memory, water-mediated, structure, and energy model (AWSEM) by adding an implicit membrane potential and reoptimizing the force field to account...

Safety approval for first Japanese reactor restarts

World Nuclear News - Wed, 07/16/2014 - 08:26
Sendai nuclear power plant units 1 and 2 have draft approval to restart and generate electricity again. The final stages in Japan's new licensing regime could be completed before September.

Ten (Warmist) Scientists Want A Meeting With Florida’s GOP Governor To Explain Climate Change

Climate Depot - Wed, 07/16/2014 - 08:09
Ten Scientists Want A Meeting With Florida’s Governor To Explain Climate Change http://thinkprogress.org/climate/2014/07/16/3460704/scientists-rick-scott-florida-letter/ Gov. Rick Scott (R-FL) CREDIT: Office of Rick Scott / Meredyth Hope Hall If you’re not a scientist, presumably you should listen to people who are when grappling with climate change. That is the logic, at least, of a group of scientists [...]
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